It's hard for the layperson to distinguish real science from cleverly
 done pseudo-science.  Sometimes the pseudo-science puts on such a 
"scientific" performance, with all the right jargon and all the right 
credentials (that of course we can't possibly confirm) and even the 
right "peer review" (again impossible to confirm). 
To
 a large extent we have to accept the authority of the scientific 
community.  Isolated "findings" that get ignored by the community are to
 be suspected, and when debunkers appear from within that community, then one feels pretty confident. 
However, as we all know, "science" can be wrong (although this is less common than many would have us think).
I
 use a few personal tests.  First, I discount personal stories and 
testimony.  It is too bad that this has to be, but it has to be.  Even 
the most honest person can have moments of delusion, moments of "filling
 in" details that aren't real (psychologists have demonstrated this many
 times).  Also of course not everyone is honest.  Liars abound, and not 
just those out for personal gain.  The history of religion is filled 
with pious frauds where the motive for the lies and exaggerations are to
 save someone's soul.
Second, I discount certain 
kinds of physical evidence that are subject to manipulation that may not
 be detectable, such as footprints and lie-detector tests and of course 
photos.
Third, I try to apply "common sense" and a sense of probability.  If something is too good to be true, it probably is.  If something is totally awe-inspiring and wondrous, I doubt.  One-headed bicyclists mistaken for two-headed bicyclists are more common than real two-headed bicyclists.
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