When science is wrong

It seems to me that there is an effort being made to justify attacking the well-established ideas of science (such as evolution, global warming, the absence of psychic stuff, the failure to find Sasquatch) on the sole and flimsy pretense that science sometimes changes its mind.  As has been noted a few times, this sort of stuff comes mainly from people who plainly know very little real science.

That made me wonder just how often science does change its mind about something important -- not what is reported in the popular press but in reality.  The only one I can think of happened early in my academic life -- the adoption of continental drift, and that idea had been supported by paleontologists for a couple decades before the evidence of shifting magnetic orientation in sea-floor deposits made the conclusion inescapable, even to the geologists.

It seems to me science as we have it is well grounded and not subject to much beyond some adjustment here and there.  It is for sure that there are extremely important unanswered questions, such as the nature of sentience, the nature of dark matter and energy, and huge issues like this, but it is unlikely the answers will involve changes in existing science.  When the answers are found, they will be pretty much new structures -- not discoveries that science is wrong somewhere but just expansions of existing knowledge.